Endocrine Abstracts

Aim: Fibroblast growth factor (FGF) 21 is a hormone which plays an important role in metabolic diseases such as diabetes, obesity and dyslipidemia. In this study; we aimed to investigate the serum total and bioactive FGF21 levels in patients with gestational diabetes mellitus (GDM) and compared with healthy pregnant controls.Material and Methods: A two-step screening method and Carpenter and Coustan criteria were used in the diagnosis of...

Aim: Olfaction and gustation have great importance on feeding behavior and food preferences. Recent published data suggests that olfaction and taste functions are modulated in response to changing levels of various molecules such as ghrelin and leptin which are play important roles on feeding and energy balance. We aimed to investigate the olfaction and taste functions in obese female patients and the association between serum ghrelin and leptin levels compared with healthy co...

Aim: Ghrelin plays an important role in stimulation of food intake and long-term regulation of body weight. In present study we aimed to investigate the effect of exenatide treatment on serum ghrelin levels in patients with type 2 diabetes.Methods: Fourteen women patients with type 2 diabetes treated with metformin and exenatide were enrolled in the study. A mixed meal test was applied to the patients while they were using their daily medications. Serum ...

Aim: In our study, we aimed to evaluate the relationship between oxidative stress markers such as total antioxidant capacity (TAC), advanced oxidant protein products (AOPP) and thiol-disulfide homeostasis parameters and diabetic peripheral neuropathy (PNP), an important microvascular complication of diabetes mellitus (DM).Material and methods: 80 (male/female=34/46) patients with type 2 DM and 19 healthy controls were included in the stu...

Aim: We aimed to investigate the possible relationship between HDL cholesterol subclasses and carotid intima media thickness (CIMT) in patients with type 1 diabetes mellitus (DM).Material and methods: Sixty-two (female/male: 33/29, mean age: 33.3±8.5 years) patients with type 1 DM at least 5 years and 20 (female/male: 10/10, mean age: 30.4±5.6 years) healthy controls were included in the study. After physical examination and anthropometric meas...

The aim of this study was to determine the relationship between biochemical parameters, parathyroid adenoma volume, and bone mineral density with respect to intact parathyroid hormone (iPTH) levels in patients with primary hyperparathyroidism. Data were collected retrospectively from patients with primary hyperparathyroidism who were diagnosed and followed-up at our clinic between 2004 and 2008. Forty-eight (female/male=42/6) patients with a mean age of 52.8±13.1 (range 2...